Alexander

Normal Pressure Hydrocephalus

Mr A is a 67 year old man who presented having been noted by his family as developing memory problems for 2-3 years with deteriorating mobility. On questioning he admitted to a number of episodes of wetting himself and being unsure of how this happened. He underwent a CT and MRI which showed a possible diagnosis of normal pressure hydrocephalus. He was admitted to hospital and had a lumbar puncture […]

Pineal Cysts

One of the most common referrals to Neurosurgeons is for evaluation of pineal cysts. The advent of widely available imaging such as MRI and CT scans has lead to a dramatic increase in findings such as this in patients who have presented often with very vague symptoms. As such they can be a diagnostic problem. By definition a pineal cyst is a benign fluid containing cyst within the tissue of the […]

Management of Brain Metastasis

Metastatic tumors are the most common neoplasm in the brain, occurring in 24-45% of all cancer patients and accounting for 20% of cancer deaths annually.  These rates are on the increase due to a boost in survival of patients with cancer because of modern therapies along with increased availability of advanced imaging techniques for early detection. Newer therapies such as immunotherapy prolong overall survival in some cancers such as Melanoma […]

Treatment of Spinal Metastases

Significant advances have been made in the  treatment of spinal metastases in recent years. Options have evolved from simple decompression surgery or conventional external bean radiotherapy (cEBRT) to complex multi-disciplinary treatments incorporating stereotactic radio surgery (SRS) and minimally invasive surgical techniques (MIS). This is important as 60% of all patients with cancer will develop spinal metastases and 5-10% will develop spinal cord compression. The aims of therapy for these patients […]

Progressive dysembryoplastic neuroepithelial tumour

An interesting article in the Journal of Clinical Neuroscience lead by Dr Hamish Alexander and co-authored by Dr Anthony Tannenburg, Dr David Walker and Dr Terry Coyne. Click here to read the full journal article Abstract: Dysembryoplastic neuroepithelial tumour (DNET) is a benign tumour characterised by cortical location and presentation with drug resistant partial seizures in children. Recently the potential for malignant transformation has been reported, however progression without malignant […]

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