Our Newro Foundation research team, Prof David Walker, Neurosurgeon and Beth Morrison, Clinical Research & Development Manager, have been working in collaboration with the School of Medicine, QIMR and the Department of Pathology, Hong Kong to research the impact of pre-therapy glioblastoma multiforme microenvironment on clinical response to autologous CMV-specific T-cell therapy.
A young lady in her early 30s presented to her GP with a short history of headaches and visual disturbance. Over a longer period of time, she had been investigated for infertility. An MRI scan of the brain revealed a large solid and cystic tumour of the 3rd ventricle. It appeared to be compressing the optic chiasm inferiorly and also causing early obstructive hydrocephalus. Below are representative images from the […]
This 50y female had been followed in our practice since 2009, when she presented with an incidental finding of a small colloid cyst of the 3rd ventricle. At the time it was not causing any hydrocephalus and a watch and wait policy was adopted. Here is an axial T2 MRI showing the cyst (small dark lesion at foramen of Monro). Over the years she had remained stable but in recent […]
A 48 year old man had been followed in our clinic for approximately 5 years. He had previously been treated at another institution after being diagnosed with a malignant glioma after suffering from seizures. After his initial presentation with seizures, he had surgical resection of a small tumour of the right frontal region, and then this was followed with radiotherapy and chemotherapy. He made a reasonable recovery from this. On […]
This 74 year old lady presented with progressive depression. She had been treated medically for months but her symptoms did not improve. She then developed headaches and cognitive deficits such as poor short term memory became increasingly obvious. An MRI scan of the brain was eventually done, revealing a very large lesion of the anterior cranial fossa. Fig 1. Preoperative MRI T1+GAD. A. Axial, B. Sagittal, C. Coronal Surgery proceeded […]